Unoziva here kuti hesperidin chii?

Ⅰ、Sumo yeHesperidin

hesperidin chimiro chechisikigo chirimwa chiri chekirasi yeflavonoid. Inowanikwa zvakanyanya mumapee emichero yecitrus yakadai seorenji peel, pomelo peel, uye lemon peel. Hesperidin ine yakasimba antioxidant, anti-inflammatory, antibacterial, antiviral uye mamwe mabasa ehupenyu, saka inoshandiswa zvakanyanya mumishonga, zvigadzirwa zvehutano, zvizoro uye mamwe minda. Hesperetin chimwe chezvinhu zvinoshanda zveorenji peel. Yakave yakaratidza kuti chimiro chayo ndeye phenolic compound. Zvimiro zvayo makristasi asina ruvara kana crystalline poda ine hwema hunonhuhwirira. Iyo yekunyunguduka i50 ℃ ~ 51 ℃ uye nzvimbo yekuvira i232 ℃. Zviri nyore kuvhuvhuta uye zvakaoma Kunyunguduka mumvura, nyore kunyungudika mune zvinonyungudutsa zvakasanganiswa senge ethanol uye ether, zvine mhedzisiro yakanaka pakurapa mite yemhuka.Kuenzaniswa neorganic phosphorus, organic nitrogen, uye organic chlorine, ine zvakanakira ine muchetura zvishoma, kusarisa kwakaderera, uye pasina kusvibiswa kwezvakatipoteredza. Kurapwa kwekiriniki, ine zvipingamupinyi zvemutengo wakakwira uye kuomerwa mukuita nyore-kushandisa-kugadzirira. Tangeretin inoshandiswa zvakanyanya mu Chemicalbook organic chemistry uye hupenyu sainzi uye mamwe minda. Nekuti zvirimo zve tangeretin muzvirimwa zvakaderera uye zvinodhura, kutsvagisa nezve tangeretin munyika yangu kunosarira kumashure. nyika yangu yakapfuma muzviwanikwa zvecitrus uye ine tarisiro yakakura yekutorwa uye kushandiswa kwe tangeretin.

Ⅱ、Kubvisa nzira yeHesperidin

hesperidin inonyanya kutorwa kubva muzvirimwa zverudzi rweRutaceae kana Euphorbiaceae. Nzira dzekubvisa dzinosanganisira recrystallization, column chromatography, high-speed countercurrent chromatography uye carbon dioxide supercritical extraction. Recrystallization nzira: Dancy orenji imhando ine mukurumbira yemacitrus yakaberekerwa kuUnited States. Tsvagiridzo yakawana kuti inotonhora-yakadzvanywa orenji mafuta akagadzirwa kubva kuDanxi maranjisi akagadzira yero precipitate mushure me centrifugation uye kwenguva refu kutonhora. Limonene yakazobviswazve uye yakadzokororwa kuti iwane chena crystalline tangeretin. Tangeretin inogadzirwa pamwe neinotonhora-yakadzvanywa tangerine oiri seyakagadzirwa-chigadzirwa, inogona kuderedza zvakanyanya mutengo wayo wekugadzira. Column chromatography: Column chromatography inoshandisa gradient elution ine yakasanganiswa organic solvents kubvisa tangeretin kubva muzvirimwa zvakaita se sweet orenji, Citrus aurantium, Danxi orenji uye Croton ine mvere shizha. High-speed counter-current chromatography: High-speed counter-current chromatography, (HSCCC kwenguva pfupi) imvura-mvura yekugovera chromatography tekinoroji. Kuenzaniswa nedzimwe nzira dzekuparadzanisa chromatographic, HSCCC haishandise chero yakasimba Chemicalbook mutakuri kana tsigiro sechikamu chakamira. Muenzaniso unongowana kupatsanurwa kwakanaka uye kugadzirira kwezvigadzirwa zvakachena munguva pfupi kuburikidza nemusiyano wekugovera pakati pemaviri-chikamu immiscible solvents. Mumakore achangopfuura, Yakagamuchira kutariswa uye kushandiswa mumunda wekubvisa zvigadzirwa zvechisikigo. Carbon dioxide supercritical extraction method: Supercritical carbon dioxide ine yakakosha kunyungudika pane zvimwe zvinhu zvakasikwa. Nheyo yekabhoni dioxide supercritical extraction tekinoroji ndeye kushandisa hukama pakati pekunyungudika kweiyo supercritical kabhoni dioxide uye density yayo, ndiko kuti, kushandisa kudzvanywa uye tembiricha kuona kunyungudika kweiyo supercritical carbon dioxide. Kufurira kwekubvisa. Mune iyo supercritical state, supercritical carbon dioxide inounzwa mukubata nezvinhu zvinopatsanurwa, kuitira kuti zvikamu zvepolarities dzakasiyana, mapoinzi ekuvira uye mamorekuru anorema anogona kutorwa zvakasarudzwa mukutevedzana, uye ipapo iyo supercritical fluid inogona kushandurwa kuita zvinwiwa zvakajairika. kuderedza kudzvinyirirwa, kuwedzera tembiricha, etc. Iyo gasi uye chinhu chakabudiswa zvakazara kana kuti zvakanyanya kunatswa, nekudaro kuzadzisa chinangwa chekuparadzanisa uye kucheneswa.

Ⅲ, Basa reHesperidin

1. Antioxidant mhedzisiro

Tangerine ine yakasimba antioxidant mhedzisiro, inogona kuchenesa mahara radicals, kuderedza oxidative kusagadzikana kuita, uye kudzivirira maseru kubva mukukuvadzwa kweiyo oxidative. Tsvagiridzo inoratidza kuti tangeretin inogona kuderedza njodzi yechirwere chemoyo, cancer uye zvimwe zvirwere uye kunonoka kuchembera.

2. Anti-inflammatory effect

Hesperidin inogona kuvharidzira mhinduro yekuputika uye kuderedza zviratidzo zvekuputika. Tsvagiridzo inoratidza kuti tangeretin inogona kuderedza kutaura kwezvinhu zvinoputika, inhibit activation yemasero anopisa, uye kuderedza kuburitswa kweanopisa vapomeri.

3. Mishonga inorwisa mabhakitiriya

Hesperidin ine yakasimba antibacterial effect uye inogona kudzivisa kukura uye kubereka kwemarudzi akasiyana-siyana ebhakitiriya. Tsvagiridzo inoratidza kuti tangeretin inogona kutadzisa kukura kweStaphylococcus aureus, Escherichia coli, Streptococcus uye mamwe mabhakitiriya epathogenic.

4. Antiviral effect

Tangerine inogona kudzivisa kukura uye kubereka kwemarudzi akasiyana-siyana evhairasi, kusanganisira utachiona hwefuruwenza, utachiona hwehepatitis B, nezvimwewo. Tsvakurudzo inoratidza kuti tangeretin inogona kukanganisa kudzokororwa kwehutachiona uye kuderedza dambudziko rehutachiona hwehutachiona.

Ⅳ,Mhedzisiro ye tangeretin

1. Lower ropa lipids

Hesperetin inogona kuderedza serum yakazara cholesterol, triglycerides uye yakaderera-density lipoprotein cholesterol mazinga uye kuwedzera yakakwirira-density lipoprotein cholesterol mazinga, nokudaro kuderedza njodzi yehutano hwemwoyo.

2. Kurwisa gomarara

Tangerine inogona kutadzisa kukura uye kuberekana kwekenza maseru uye kusimudzira apoptosis yebundu masero, nekudaro kuve neanorwisa kenza. Zvidzidzo zvakaratidza kuti tangeretin ine yakakosha inhibitory mhedzisiro pamakenza akasiyana senge colorectal cancer, cancer yemapapu, uye kenza yemazamu.

3. Chengetedza chiropa

Tangerine inogona kuderedza kukuvara kwechiropa uye kukurudzira kuvandudzwa uye kugadziriswa kwemasero echiropa, nekudaro kudzivirira chiropa. Zvidzidzo zvakaratidza kuti tangeretin inogona kuderedza oxidative kusagadzikana mhinduro yechiropa uye kuderedza dhigirii rekukuvara kwechiropa.

4. Anti-diabetes

Hesperetin ine anti-diabetic properties nekudzikisa mazinga ehuga uye nekuvandudza insulin senitivity. Tsvagiridzo inoratidza kuti tangeretin inogona kuderedza kunyura uye kushandiswa kweglucose uye kukurudzira kuvanzika uye kushandiswa kwe insulin.

Ⅴ、Kushandiswa kweHesperidin

1.Pharmaceutical field

Hesperetin inoshandiswa zvakanyanya mundima yekurapa seyanobatsira kurapa kwezvirwere zvakasiyana senge antioxidant, anti-inflammatory, antibacterial, uye antiviral. Semuenzaniso, tangeretin inogona kuderedza njodzi yechirwere chemoyo, kenza, chirwere cheshuga nezvimwe zvirwere uye kukurudzira kupora kwemurwere.

2. Munda wezvigadzirwa zvehutano

Hesperetin inoshandiswa zvakanyanya mumunda wezvigadzirwa zvehutano sechinhu chikuru chezvigadzirwa zvehutano. Semuenzaniso, tangeretin inogona kunonoka kuchembera, kuvandudza hutachiona, kukurudzira kurara, nezvimwewo, uye yave imwe yezvinowanzoshandiswa zvehutano zvigadzirwa zvevanhu vemazuva ano.

3. Cosmetics munda

Hesperetin inoshandiswa zvakanyanya mumunda wezvizoro sechinhu chikuru chezvizoro. Semuenzaniso, tangeretin ine maitiro akawanda akadai se antioxidant, anti-inflammatory, antibacterial, uye antiviral, uye yave imwe yezvinhu zvakakosha zvezvizoro.

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